Santa Fe acts as both New Mexico’s political and creative capital: Wander its wide streets, flanked by adobe houses, and you’ll begin to see why artists like Georgia O’Keeffe were so inspired by this eclectic, historic town. (Traveler readers also can’t stay away—Santa Fe is a regular on our best-of-the-U.S. list.) The city’s many art institutions, 250-plus galleries (notably SITE Santa Fe, in the Railyard, an emerging contemporary arts hub), and Spanish colonial churches keep culture fiends busy. To recharge after an active day of museum-hopping, contributing editor Alex Postman recommends ordering 505 Manhattans at Radish & Rye, whose 75 bourbons and whiskeys are an antidote to tequila overload, and a meal at Eloisa, where John Rivera Sedlar, whose great aunt was O’Keeffe’s chef, serves up a mean duck enfrijolada.
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